There’s something irresistibly comforting about layers of creamy sauce and tender chicken wrapped up in pasta — that’s why I can’t get enough of this Creamy Chicken Alfredo Lasagna Roll Ups Recipe. Every bite feels indulgent but still homey, perfect for a cozy night in or impressing folks at dinner.

A close-up of a creamy lasagna roll showing three visible layers: the top layer is golden brown melted cheese with small green herb pieces sprinkled on it, the middle layer is soft ruffled yellow pasta, and the bottom layer is thick white cheese sauce with black pepper bits, melting and dripping down from the roll. The lasagna roll is held by a wooden spatula against a white marbled background. Photo taken with an iphone --ar 2:3 --v 7

Jump to:

Why You'll Love This Recipe
Ingredients & Why They Work
Make It Your Way
Step-by-Step: How I Make Creamy Chicken Alfredo Lasagna Roll Ups Recipe
Top Tip
How to Serve Creamy Chicken Alfredo Lasagna Roll Ups Recipe
Make Ahead and Storage
Frequently Asked Questions:
Final Thoughts
Creamy Chicken Alfredo Lasagna Roll Ups Recipe

Why You'll Love This Recipe

I can honestly say this Creamy Chicken Alfredo Lasagna Roll Ups Recipe has become one of my go-to dishes when I want something that tastes fancy but is actually pretty simple to pull together. The creamy sauce paired with shredded chicken feels like a hug in food form — and the roll ups add a fun, elegant twist that everyone at the table enjoys.

Comfort food with a twist: Roll ups are an inviting change from traditional lasagna that are just as rich and delicious.
Simple ingredients, big flavor: The combination of creamy Alfredo sauce and tender chicken makes every bite flavorful without complicated prep.
Easy to serve and portion: Roll ups make great individual servings, perfect for family dinners or meal prep.
Customizable and forgiving: Whether you add more cheese, swap chicken for veggies, or sprinkle fresh herbs, this recipe is totally adaptable.

A white baking dish holds a baked dish made of six rolled layers filled with a light creamy filling visible at the edges. The top layer is a golden-brown melted cheese with scattered green herb bits, showing a slightly bubbly and browned texture. The layers below are soft yellow pasta sheets with a smooth cream sauce visible around the edges. The dish rests on a white marbled surface photo taken with an iphone --ar 2:3 --v 7

Ingredients & Why They Work

Each ingredient in this dish plays a starring role — the creamy Alfredo sauce clings perfectly to the pasta, while the shredded chicken adds substance and protein. When you combine them in roll ups, you get a harmonious blend of texture and flavor. I always recommend picking a good-quality parmesan and fresh garlic, since they really elevate the sauce with depth and richness.

Flat lay of uncooked flat rectangular lasagna noodles neatly stacked, a stick of pale yellow butter, three whole uncracked brown garlic cloves, a small mound of finely ground white all-purpose flour on a white ceramic plate, small white bowls holding creamy whole milk and thick heavy whipping cream, a heap of finely grated parmesan cheese, a bowl with shredded cooked white chicken breast, shredded white mozzarella cheese pile, a small bunch of bright green chopped fresh parsley, and a small white bowl with ground black pepper next to a pinch of fine salt and a tiny amount of ground nutmeg powder on a simple white ceramic dish, all arranged with perfect symmetry and balanced proportions, placed on a clean white marble surface, soft natural light, photo taken with an iPhone, professional food photography style, fresh ingredients, white ceramic bowls, no bottles, no duplicates, no utensils, no packaging --ar 2:3 --v 7 --p m7354615311229779997

Lasagna noodles: The wide noodles are ideal for rolling and hold the filling well without falling apart. Cooking al dente ensures they don’t get mushy.
Butter: Adds richness and helps create the base for the roux that thickens the sauce.
Garlic: Fresh garlic sautéed in butter provides a fragrant foundation that makes the Alfredo sauce sing.
All-purpose flour: Helps thicken the sauce to that perfectly creamy consistency.
Milk (2% or whole) & heavy whipping cream: Combining these gives the sauce a luscious, silky texture without being too heavy or too thin.
Parmesan cheese: The star cheese for Alfredo, offering sharp, nutty flavor and richness.
Salt, pepper & nutmeg: Essential seasonings; nutmeg adds a subtle warmth that enhances the sauce without overpowering.
Cooked shredded chicken: A tender, protein-packed filling that pairs beautifully with the creamy sauce.
Mozzarella cheese: Melts beautifully and adds gooeyness for that wonderful cheesy pull.
Fresh parsley: For a pop of color and bright herbal contrast, just before serving.

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Note: You'll find the complete list of ingredients, along with their exact measurements, in the printable recipe card at the bottom of this post.

Make It Your Way

One of my favorite things about the Creamy Chicken Alfredo Lasagna Roll Ups Recipe is how easy it is to tweak based on what you have or your dietary preferences. I often add sautéed spinach or mushrooms to the filling for a veggie boost, and sometimes swap half the mozzarella for fontina for a nuttier melt.

Variation: When I've had leftover turkey instead of chicken, it works just as well — especially after shredding and tossing in the sauce.
Dietary modification: I’ve experimented with gluten-free noodles and it’s a decent swap, just be gentle when rolling to avoid breaks.
Flavor boost: Try stirring in a little cooked bacon or Italian seasoning to the sauce for an extra punch.

Step-by-Step: How I Make Creamy Chicken Alfredo Lasagna Roll Ups Recipe

Step 1: Perfectly Cook the Noodles

Start by boiling your lasagna noodles according to the package instructions, but make sure to cook them al dente (still a slight bite to them). I add a teaspoon of salt to the water because it seasons the noodles nicely. Once cooked, drain them and immediately transfer to a pot with room temperature water — this little trick stops them from sticking together and keeps them pliable for rolling later.

Step 2: Make the Creamy Alfredo Sauce

In a medium saucepan over medium heat, melt the butter until it foams slightly. Add minced garlic and sauté just until fragrant — about a minute — so it doesn’t burn. Next, sprinkle in the flour and whisk constantly for another minute; this cooks out the raw flour taste. Slowly pour in the milk and heavy cream, whisking continuously. Let it come to a gentle simmer for about 2 minutes until it thickens.

Turn off heat and stir in the parmesan cheese, salt, pepper, and a pinch of nutmeg if you like that extra warmth. Whisk until the cheese melts and the sauce is velvety smooth. If it feels too thick, just thin it a little with more milk.

Step 3: Assemble the Roll Ups

Lightly coat the bottom of a baking dish with about half a cup of Alfredo sauce to prevent sticking. In a bowl, mix together 1 cup of the Alfredo sauce with shredded chicken and 1 cup of mozzarella cheese, seasoning with a pinch of salt and pepper for balance.

Lay one noodle flat on a clean surface, spoon a generous layer of the chicken mixture along its length, then carefully roll it up. Place seam side down in the baking dish. Repeat with the remaining noodles and filling.

Step 4: Bake Until Golden and Bubbling

Pour the rest of the Alfredo sauce evenly over the roll ups, and sprinkle the remaining mozzarella cheese on top. Bake in a preheated oven at 375°F (190°C) for about 25–30 minutes, until the sauce is bubbly and the cheese is golden brown. The smell that fills your kitchen at this point? Pure comfort heaven.

Top Tip

From making this dish dozens of times, I’ve learned a few tricks that make all the difference. These tips will help you nail the texture and flavor every time without stress.

Don’t overcook your noodles: This keeps them from becoming mushy and makes rolling easier.
Sauté garlic gently: Burnt garlic will give a bitter taste, so keep the heat medium and watch carefully.
Mix cheese into sauce while warm: This helps it melt perfectly and prevents clumping.
Cover with foil if browning too fast: If the top melts and browns before the sauce bubbles, loosely tent foil to finish baking without drying out.

How to Serve Creamy Chicken Alfredo Lasagna Roll Ups Recipe

chicken alfredo lasagna - Serving Suggestion

Garnishes

I always finish mine with a sprinkle of fresh chopped parsley — it adds a burst of color and a subtle, fresh brightness that cuts through the richness. Sometimes I toss on a little extra parmesan or cracked black pepper for that added flair.

Side Dishes

This dish pairs wonderfully with a crisp green salad dressed lightly with lemon vinaigrette or roasted garlic green beans for a touch of freshness. I also love serving it alongside garlic bread to sop up every last bit of the creamy sauce.

Creative Ways to Present

For special occasions, I’ve arranged these roll ups upright in a round casserole dish, sprinkled with extra herbs and breadcrumbs for crunch. It’s a fun presentation that invites guests to serve themselves a perfect portion—and they always ask for seconds!

Make Ahead and Storage

Storing Leftovers

I let leftovers cool completely, then cover the baking dish tightly with foil or transfer individual roll ups to an airtight container. Stored in the fridge, they keep beautifully for 3–4 days without drying out or losing flavor.

Freezing

This recipe freezes surprisingly well. I wrap each roll up tightly in plastic wrap and place them in a freezer-safe bag or container. When you’re ready, thaw overnight in the fridge and then bake as usual—might take a few extra minutes but still delicious!

Reheating

To reheat, I cover leftovers with foil and warm in the oven at 350°F (175°C) for about 15–20 minutes. This keeps the roll ups moist and prevents the cheese from over-browning. Microwaving works in a pinch, but the oven method preserves the texture beautifully.

Frequently Asked Questions:

Can I use different types of cheese in this recipe?

Absolutely! While mozzarella and parmesan are classic here, feel free to substitute or add cheeses like fontina, provolone, or asiago for different flavors and textures. Just make sure they melt well for that creamy roll-up experience.

Is it okay to prepare this recipe ahead of time?

Yes, you can assemble the roll ups a day before baking. Just cover and refrigerate the dish, then bake right before serving. It’s a great way to save time on busy days or before hosting guests.

Can I swap chicken for a vegetarian option?

Definitely! For a vegetarian twist, replace the chicken with sautéed mushrooms, spinach, or a mix of your favorite roasted veggies. The creamy Alfredo sauce keeps the dish satisfying and delicious even without meat.

What’s the best way to avoid dry noodles in this recipe?

The key is not to overcook the lasagna noodles (cook them al dente) and to keep them separated in room temperature water after draining. Also, generously spooning Alfredo sauce inside and over the roll ups helps keep everything moist and creamy during baking.

Final Thoughts

This Creamy Chicken Alfredo Lasagna Roll Ups Recipe has truly become one of those comfort dishes I reach for again and again — whether I’m feeding family or hosting friends. It’s special enough to feel like a celebration, but forgiving enough to be stress-free in the kitchen. Give it a try like I’m handing you a plate warm from my oven; I promise you’ll be smitten with its creamy, cheesy goodness and the way it brings everyone together at the table.